Search results for " Biological application"

showing 3 items of 3 documents

LbL multilayer capsules: recent progress and future outlook for their use in life sciences.

2010

In this review we provide an overview of the recent progress in designing composite polymer capsules based on the Layer-by-Layer (LbL) technology demonstrated so far in material science, focusing on their potential applications in medicine, drug delivery and catalysis. The benefits and limits of current systems are discussed and the perspectives on emerging strategies for designing novel classes of therapeutic vehicles are highlighted. © 2010 The Royal Society of Chemistry.

Materials scienceDrug Delivery SystemsPharmaceutical PreparationsPolymersComposite polymerDrug deliveryGeneral Materials ScienceNanotechnologyCapsuleslayer-by-layer; polymer capsules; biological applicationsBiological Science DisciplinesCatalysisNanoscale
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Rapid and eco-friendly synthesis of graphene oxide-silica nanohybrids

2014

The increasing interest in Graphene oxide (GO) is due to many issues: the presence of both sp2-conjugated atoms and oxygen-containing functional groups provides a strong hydrophilicity and the possibility to further functionalize it with other molecules (i.e. π-π interactions covalent attachment etc.) [1]. Furthermore since the GO is biocompatible and noncytotoxic many studies have been recently focused on the development of GO-based nanodevices for bioimaging DNA detection drug delivery. Due to their low cytotoxicity and large internal surface area silica nanoparticles have been taken into account as promising material for biolabeling and drug loading/delivery. Particular consideration has recently been demonstrated for GO-silica composites because of the potentialities for electrical applications their chemical inertia and stability toward ions exposure. The possibility to combine the extraordinary properties of GO and silica offers several advantages for the realization of nanoprobes for biological applications and of biosensor [12]. The strategy for the fabrication of GO-nanosilica nanohybrids can be schematized as follows: (i) synthesis of GO by oxidizing graphite powder with the method described by Marcano et al. [3] (ii) Preparation of oxygen-loaded silica nanoparticles by thermal treatments in controlled atmosphere in order to induce high NIR emission at 1272 nm from high purity silica nanoparticles. (iii) preparation of GrO-silica nanohybrid films via rapid solvent casting in water. The nanohybrids were tested by XPS FTIR Raman analysis UV photoluminescence analysis TGA Zeta potential measurements electrical tests AFM and SEM. Several nanohybrids were prepared by combining two different typologies of GO and two different samples of silica.
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Nanohydrogel Formation within the Halloysite Lumen for Triggered and Sustained Release

2018

An easy strategy to obtain nanohydrogels within the halloysite nanotube (HNTs) lumen was investigated. Inorganic reverse micelles based on HNTs and hexadecyltrimethylammonium bromides were dispersed in chloroform, and the hydrophilic cavity was used as a nanoreactor to confine the gel formation based on alginate cross-linked by calcium ions. Spectroscopy and electron microscopy experiments proved the confinement of the polymer into the HNT lumen and the formation of calcium-mediated networks. Biological tests proved the biocompatibility of the hybrid hydrogel. The nanogel in HNTs was suitable for drug loading and sustained release with the opportunity of triggered burst release by chemical …

NanotubeMaterials scienceBiocompatibilityChlorine compound02 engineering and technologyNanoreactorHexadecyl trimethyl ammonium bromideengineering.materialHybrid hydrogel010402 general chemistry01 natural sciencesMicelleHalloysiteSustained release Drug deliveryAdsorptionKaoliniteHalloysite nanotube (HNTs)Chemical stimuliGeneral Materials ScienceControlled drug deliveryBiological testSettore CHIM/02 - Chimica Fisicachemistry.chemical_classificationTargeted drug deliveryCrosslinkingReverse micellePolymer021001 nanoscience & nanotechnology0104 chemical sciencesChemical engineeringchemistryYarn Biological applicationengineeringBiocompatibilityCalcium0210 nano-technologyMicelleNanogelACS Applied Materials & Interfaces
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